Neurobiology of Alcohol Use Disorder University of Gothenburg Sweden

Neurobiology of alcohol use disorder
using Operant Self-Administration
Model in Rats

Alcohol Use Disorder (AUD) is a comorbid and highly prevalent disorder, causing severe health
problems for individual and high costs to the society. Existing pharmacotherapy has shown limited
efficacy and therefore further investigation of possible neurochemical targets of alcohol are warranted
and could lead to new pharmacological interventions.

The current project aims to reveal the underlying neural circuits regulating AUD and identifying new
treatments of AUD using the operant slef-administration model in rats. The postdocral fellow will work
under the research umbrella of Associate professors Jerlhag, Ericson and Adermark.
Initially, the postdoctoral fellow will have the unique opportunity to continue to set up the operant selfadministration

model in the lab (at the addiction biology Unit/department of pharmacology at
University of Gothenburg, Sweden). Following ethical approval, the postdoctoral fellow will run
experiments in the operant self administration model where the efficacy of novel pharmacological
treatments, which mainly are based on other preclinical studies, will be explored.

This postdoctoral stipend is funded collectivelt by Associate professor Jerlhag, Ericson and
Adermark. This is an research intensive workplace with ample opportunities for interaction with other
research groups within the field of pharmacology, psychiatry, neurobiology and neuropharmacology.
The postdoctoral fellow will also have close contact with researchers from other departments and
universities in Sweden and abroad.

We are looking for a candidate with a strong interest in the neurobiology of AUD. A suitable
candidate has a solid neuroscience background, and preferentially previous experience of operant
self-administration model. In addition, experience of preclinical behavioral studies in mice and rats
are merited skills. Good communication, scientific writing and presentation skills, scientific integrity,
and personal suitability with the rest of the research team are necessary.
Send your application including a personal letter, CV and PhD certificate to
elisabet.jerlhag@pharm.gu.se before 31st of December 2018.


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