Post-Doctoral in Translational NeuroScience (University of Barcelona Institute of Neurosciences)

Are you a postdoctoral researcher thinking about your next career move? The Junior Leader Incoming Fellowships are a great option if you are an experienced researcher looking to give your career a boost by working abroad. Institut of Neurosciences of the University of Barcelona allows you to work in a first class research environment while benefitting from an attractive salary to cover living, travel and family and research costs. Group and project information Applicants will be integrated into the research group “Hippocampal function in health and disease”; (P.I. Albert Giralt). One of the aims of our research group is to evaluate the role of a family of transcription factors in the communication between the immune and central nervous system in the context of schizophrenia. To this aim, the main objectives for the candidate will be: -To determine the contribution of this family of genes to the immune alterations present in a cohort of schizophrenic patients (up to 200 patients). -To assess the relative importance of immune vs neural effects of this family of genes to the behavioral and molecular hallmarks of schizophrenia. To accomplish with these aims, the candidate will work using human blood samples from schizophrenia patients and human postmortem brain samples from controls and patients too. Mouse primary neurons or differentiated iPSCs to neurons will be also used. In vivo experiments with mutliple lines of genetically modified mice for this family of genes will also be performed. Complex statistical analysis will be carried out comparing results obtained from experiments using human samples with several clinical scores from patients. The use of brain organoids are also possible. Benefits Working conditions: Three maximum annual payments of €97,500 which include labor costs €59,000; annual research project costs €38,500; gross annual family assistance €1,200 and mobility assistance €5,400 Duration: 3 years Full time temporary contract Starting date: flexible from beginning of April 2020 Selection process Additional comments How to apply Please submit your CV to: Albert Giralt (albertgiralt@ub.edu); Reference: Junior Leader Candidate -A letter of motivation would be appreciated -A recommendation letter would be highly appreciated Offer Requirements Skills/Qualifications Skills/Qualifications: -Priority: Skills in cultures of human and mouse immune cells (T-Cells, B-Cells, monocytes, macrophages, etc...) and their characterization. -Priority: Molecular biology skills (Q-PCR, PCR..) -Priority: FACS -Secondary: Experience on iPSCs -Secondary: Experience on analysing microarray and RNAseq data -Secondary: Immunofluorescence -Secondary: Western Blot -Secondary: Confocal microscopy Languages: English: Excellent Specific Requirements Specific Requirements: Candidates should have earned their doctoral degree 2 to 7 years prior to 8 October. Candidates must not have resided or have carried out their main activity (work, studies, etc.) in Spain for more than 12 months in the 3 years immediately preceding October 8. Short stays, such as holidays, will not be taken into account. If you apply for this position please say you saw it on Psychoneuroxy

Are you a postdoctoral researcher thinking about your next career move? The Junior Leader Incoming Fellowships are a great option if you are an experienced researcher looking to give your career a boost by working abroad. Institut of Neurosciences of the University of Barcelona allows you to work in a first class research environment while benefitting from an attractive salary to cover living, travel and family and research costs.

Group and project information

Applicants will be integrated into the research group “Hippocampal function in health and disease”; (P.I. Albert Giralt).

One of the aims of our research group is to evaluate the role of a family of transcription factors in the communication between the immune and central nervous system in the context of schizophrenia. To this aim, the main objectives for the candidate will be:

-To determine the contribution of this family of genes to the immune alterations present in a cohort of schizophrenic patients (up to 200 patients).

-To assess the relative importance of immune vs neural effects of this family of genes to the behavioral and molecular hallmarks of schizophrenia.

To accomplish with these aims, the candidate will work using human blood samples from schizophrenia patients and human postmortem brain samples from controls and patients too. Mouse primary neurons or differentiated iPSCs to neurons will be also used. In vivo experiments with mutliple lines of genetically modified mice for this family of genes will also be performed. Complex statistical analysis will be carried out comparing results obtained from experiments using human samples with several clinical scores from patients. The use of brain organoids are also possible.

Benefits

Working conditions:

Three maximum annual payments of €97,500 which include labor costs €59,000; annual research project costs €38,500; gross annual family assistance €1,200 and mobility assistance €5,400
Duration: 3 years
Full time temporary contract
Starting date: flexible from beginning of April 2020

Selection process

Additional comments

How to apply

Please submit your CV to: Albert Giralt (albertgiralt@ub.edu); Reference: Junior Leader Candidate

-A letter of motivation would be appreciated

-A recommendation letter would be highly appreciated

Offer Requirements

Skills/Qualifications

Skills/Qualifications:

-Priority: Skills in cultures of human and mouse immune cells (T-Cells, B-Cells, monocytes, macrophages, etc...) and their characterization.

-Priority: Molecular biology skills (Q-PCR, PCR..)

-Priority: FACS

-Secondary: Experience on iPSCs

-Secondary: Experience on analysing microarray and RNAseq data

-Secondary: Immunofluorescence

-Secondary: Western Blot

-Secondary: Confocal microscopy

Languages:

English: Excellent

Specific Requirements

Specific Requirements:

Candidates should have earned their doctoral degree 2 to 7 years prior to 8 October.
Candidates must not have resided or have carried out their main activity (work, studies, etc.) in Spain for more than 12 months in the 3 years immediately preceding October 8. Short stays, such as holidays, will not be taken into account.

If you apply for this position please say you saw it on Psychoneuroxy

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