PhD Position in Developmental Neuroscience Ludwig Maximilians University of Munich

PhD position in Developmental Neuroscience (m/f/d) 65% Einrichtung: Medizinische Fakultät (Biomedizinisches Centrum) Besetzungsdatum: as soon as possible Ende der Bewerbungsfrist: 01.05.2020 Entgeltgruppe: TV-L Befristung: 3 years Es handelt sich um eine Teilzeitstelle. (Stundenzahl: 65%) Die Ludwig-Maximilians-Universität München (LMU) ist eine der renommiertesten und größten Universitäten Deutschlands. Aufgaben Our research group focusses on the molecular basis of synapse formation in the central nervous system. The successful candidate will employ state-of-the-art experimental approaches to study the development of synapses in wildtype and transgenic mice. The project will be a continuation of previous studies (Handara et al., (2019) The role of agrin, Lrp4 and MuSK during dendritic arborization and synaptogenesis in cultured embryonic CNS neurons. Developmental Biology 445: 54-67; Handara & Kröger (2019) Alternative splicing and the intracellular domain mediate TM-agrin's ability to differentially regulate the density of excitatory and inhibitory synapse-like specializations in developing CNS neurons. Neuroscience 419: 60-71; Karakatsani et al., (2017). Neuronal LRP4 regulates synapse formation in the developing CNS. Development 144, 4604-4615.) and will involve high-resolution confocal microscopy, electrophysiology, biochemistry and molecular biology. The Ludwig-Maximilians-Universität München (LMU) is one of the most renowned Universities in Europe. The Department of Physiological Genomics (http://www.genom.physiol.med.uni-muenchen.de/research_gr/index.html) is located in the new Biomedical Center of the LMU Munich (http://www.bmc.med.uni-muenchen.de) and offers excellent training and support in a highly stimulatory scientific environment. The salary will be 65% TVL. Anforderungen We are seeking a highly-motivated candidate for our team. Prior experiences in molecular and cellular neuroscience, analysis and breeding of transgenic mice as well as interest and basic knowledge in Developmental Neuroscience are advantageous. Excellent communication skills in English (oral and written) are required. Basic German language skills are beneficial. Wir bieten Ihnen eine interessante und verantwortungsvolle Tätigkeit mit guten Weiterbildungs- und Entwicklungsmöglichkeiten. Schwerbehinderte Personen werden bei ansonsten im Wesentlichen gleicher Eignung bevorzugt. Die Bewerbung von Frauen wird begrüßt. Weitere Informationen http://www.genom.physiol.med.uni-muenchen.de/research_gr/kroeger_group/index.html Bewerbungsadresse Prof. Dr. Stephan Kröger Biomedical Center Department of Physiological Genomics Großhaderner Str. 9 82152 Planegg-Martinsried E-Mail: skroeger@lmu.de Ansprechpartner/in Prof. Dr. Stephan Kröger Phone: +49 89 2180 71899 If you apply for this position please say you saw it on Psychoneuroxy

PhD position in Developmental Neuroscience (m/f/d) 65%

Einrichtung: Medizinische Fakultät
(Biomedizinisches Centrum)
Besetzungsdatum: as soon as possible
Ende der Bewerbungsfrist: 01.05.2020
Entgeltgruppe: TV-L
Befristung: 3 years

Es handelt sich um eine Teilzeitstelle. (Stundenzahl: 65%)

Die Ludwig-Maximilians-Universität München (LMU) ist eine der renommiertesten und größten Universitäten Deutschlands.

Aufgaben

Our research group focusses on the molecular basis of synapse formation in the central nervous system. The successful candidate will employ state-of-the-art experimental approaches to study the development of synapses in wildtype and transgenic mice. The project will be a continuation of previous studies (Handara et al., (2019) The role of agrin, Lrp4 and MuSK during dendritic arborization and synaptogenesis in cultured embryonic CNS neurons. Developmental Biology 445: 54-67; Handara & Kröger (2019) Alternative splicing and the intracellular domain mediate TM-agrin's ability to differentially regulate the density of excitatory and inhibitory synapse-like specializations in developing CNS neurons. Neuroscience 419: 60-71; Karakatsani et al., (2017). Neuronal LRP4 regulates synapse formation in the developing CNS. Development 144, 4604-4615.) and will involve high-resolution confocal microscopy, electrophysiology, biochemistry and molecular biology.
The Ludwig-Maximilians-Universität München (LMU) is one of the most renowned Universities in Europe. The Department of Physiological Genomics (http://www.genom.physiol.med.uni-muenchen.de/research_gr/index.html) is located in the new Biomedical Center of the LMU Munich (http://www.bmc.med.uni-muenchen.de) and offers excellent training and support in a highly stimulatory scientific environment. The salary will be 65% TVL.

Anforderungen

We are seeking a highly-motivated candidate for our team. Prior experiences in molecular and cellular neuroscience, analysis and breeding of transgenic mice as well as interest and basic knowledge in Developmental Neuroscience are advantageous. Excellent communication skills in English (oral and written) are required. Basic German language skills are beneficial.

Wir bieten Ihnen eine interessante und verantwortungsvolle Tätigkeit mit guten Weiterbildungs- und Entwicklungsmöglichkeiten. Schwerbehinderte Personen werden bei ansonsten im Wesentlichen gleicher Eignung bevorzugt. Die Bewerbung von Frauen wird begrüßt.