The Meletis laboratory, in the Department of Neuroscience, has an open position for a postdoctoral fellow to investigate the function of neuron subtypes during motivated behavior and decision-making, including circuit dysfunction in mouse models of stress and mood disorders. Your missionThe research will focus on the functional investigation of neurons and circuits during motivated behaviors through a number of advanced circuit approaches to target, record and manipulate molecularly defined neurons. The project will address the in vivo role of molecularly defined neuron subtypes in the basal ganglia, hypothalamus, and the lateral habenula. The project will involve the use and development of genetically modified mice to target neuron subtypes using in vivo optogenetics and behavioral paradigms (freely moving and head-fixed) to define the contribution of specific circuits to motivated and aversive behavior. The project will benefit from ongoing projects that have established the identity and connectivity of neuron subtypes in relevant circuits based on single cell RNA-seq and monosynaptic rabies tracing. Successful applicants will have the opportunity to work in a stimulating and collaborative environment with state-of-the-art infrastructure. We expect applicants to have a strong determination to reveal the function of neurons and circuits during behavior, with extensive experience and interest in behavior, imaging/optical methods and/or electrophysiology. Advanced knowledge in quantitative methods, statistics and programming, are required. Your profileTo be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a Swedish doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier. What do we offer?A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.
ApplicationAn employment application must contain the following documents in English or Swedish:
Welcome to apply at the latest October 28th, 2024 The application is to be submitted through the Varbi recruitment system.
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